It doesn’t happen terribly often, but every now and then humor slides into aerospace concept art. I’m ~100% sure that that’s exactly what this is: Expulsive Nuclear-Electric Manned Astroliner (ENEMA). Convair/General Dynamic artist’s concept, 1960-62. The design is actually not that unlike some nuclear launch vehicle concepts of the time, with one giant nuclear engine connected to one giant spherical tank, topped by a payload… but come on, we all know what they were going for here.
Click image to go to a Flickr page with a really high rez version.
