A groundbreaking study by Cuttler et al. (2024) found that CBG significantly reduces anxiety and stress while enhancing verbal memory, without signs of cognitive impairment. This dual action of anxiety reduction and cognitive enhancement sets CBG apart from many traditional anti-anxiety medications.
For those battling neurodegenerative diseases, CBG offers a glimmer of hope. Research indicates that CBG may help protect neurons from damage, potentially slowing the progression of conditions like Huntington’s disease and Parkinson’s.
2024. Acute Effects of Cannabigerol on Anxiety, Stress, and Mood: A Double-Blind, Placebo-Controlled, Crossover, Field Trial This clinical trial found that CBG significantly reduces anxiety and stress, while enhancing verbal memory, with no cognitive impairment or subjective drug effects.
2021. Clinical Insights Into Cannabinoids: Exploring the Potential of CBG for Anxiety and Stress
This article discusses CBG’s potential benefits for managing anxiety and stress, with insights from recent clinical research.
2010. Pharmacological Properties of CBG: Targeting Serotonergic and Adrenergic Receptors
This review covers CBG’s interactions with serotonin and adrenergic receptors, which are closely tied to anxiety and depression, highlighting its mood-regulating potential.
2005. Differential Effects of CBG and CBD at the 5-HT1A Receptor
This study explores how CBG acts as an antagonist at the serotonin receptor 5-HT1A, a key receptor involved in mood regulation, which is important in managing anxiety and depression.
Additional Resource:
Our deep-dive article with video on CBD FOR ANXIETY
2021. Cannabinoid Therapies: Exploring CBG for Neuroprotection and Anti-Inflammatory Effects
This study explores the neuroprotective potential of CBG, with specific attention to neurodegenerative diseases such as Parkinson’s and Huntington’s.
2019. CBG and Neurodegenerative Diseases: A Review of Preclinical Evidence
This review discusses preclinical evidence on how CBG may benefit individuals with neurodegenerative diseases, including Huntington’s disease, by protecting neuronal cells from damage.
Studies reveal CBG’s potential to reduce pain without the high associated with THC. Its anti-inflammatory effects could make it a natural alternative to over-the-counter pain medications.
Barradas et al. (2024) demonstrated CBG’s effectiveness in reducing both acute and chronic pain in animal models, particularly in cases of neuropathic pain.
Giacoppo et al., 2020. CBG’s Antibacterial and Antimicrobial Properties: A New Frontier in Antibiotics
This study highlights CBG’s broad-spectrum antibacterial and anti-inflammatory properties, contributing to its pain-relieving potential.
Farha et al., 2020. Uncovering the Hidden Antibiotic Potential of CBG
Besides its antibacterial properties, this study discusses CBG’s anti-inflammatory effects, which contribute to its pain-relief capabilities.
Pollastro et al., 2011. CBG Activation of TRP Channels and Its Role in Pain Management
This study focuses on how CBG interacts with TRP channels involved in pain perception, highlighting its role in managing pain. These channels are involved in pain perception and inflammation, hinting at CBG’s potential as a novel approach to managing chronic pain conditions.
Pollastro et al., 2011. CBG’s Interaction with TRP Channels
This research investigates CBG’s ability to activate various TRP channels, which play a role in both pain perception and inflammation.
Research suggests that CBG can reduce intraocular pressure, making it beneficial for glaucoma patients.
Colasanti, B.K., 1990. A comparison of the ocular and central effects of Δ9-tetrahydrocannabinol and cannabigerol. Journal of Ocular Pharmacology and Therapeutics, 6(4), pp.259-269.
Department of Ophthalmology, West Virginia University Health Sciences Center, 1990. Study on CBG and intraocular pressure.
This study demonstrated that CBG significantly reduced intraocular pressure in animal models, suggesting that it has therapeutic potential for glaucoma.
University of British Columbia, 2018. Research on CBGA eye drops for glaucoma.
CBG has shown positive results in animal studies for reducing IBD symptoms.
Recent research has unveiled CBG’s potential benefits for heart health. Vernail et al. (2022) found that CBG administration lowered blood pressure in mice by activating α2-adrenoreceptors. This suggests that CBG could play a role in managing hypertension and other cardiovascular issues, without the psychoactive effects associated with some cannabis-derived compounds.
While still in early stages, research on CBG’s potential anti-cancer properties is promising. Nabissi et al. (2018) demonstrated that CBG could inhibit colorectal cancer cell growth in preclinical studies. While it’s crucial not to overstate these findings, they do open up new avenues for cancer research and potential therapeutic strategies.
2021. Cannabigerol’s Anti-Cancer Potential: Insights From Preclinical Studies
This report from the National Cancer Institute includes information on CBG’s effects on cancer cell growth, particularly in colon cancer models, suggesting future potential as a cancer therapeutic.
2018. Cannabigerol as a Therapeutic Option for Colorectal Cancer
A preclinical study that shows CBG inhibits colorectal cancer cell growth, indicating its potential as a treatment option for colorectal cancer.
1998. Antitumor Activity of Cannabigerol Against Human Oral Epitheloid Carcinoma Cells
This early study demonstrated that CBG could inhibit the growth of certain cancer cell lines, pointing toward its potential as an anticancer agent.
In an era of increasing antibiotic resistance, CBG’s antimicrobial properties are particularly exciting.
Löfke et al. (2020) highlighted CBG’s broad-spectrum antibacterial effects, especially against biofilm-forming bacteria and MRSA.
This discovery positions CBG as a potential ally in the fight against stubborn bacterial infections, offering hope where traditional antibiotics fall short.
2020. Uncovering the Hidden Antibiotic Potential of CBG
This research demonstrates CBG’s powerful antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), suggesting that CBG could be a viable alternative to traditional antibiotics.
2020. CBG’s Antibacterial and Antimicrobial Properties: A New Frontier in Antibiotics
This study highlights CBG’s broad-spectrum antibacterial properties, particularly its effectiveness against both gram-negative and gram-positive bacteria.
2020. CBG’s Effect on Bacterial Infections and Antibiotic Resistance
This article discusses CBG’s potential in combating antibiotic-resistant bacteria, specifically focusing on its effectiveness against MRSA.
CBG’s anti-inflammatory and antibacterial properties make it an intriguing candidate for skincare applications. Early research suggests that CBG may help in managing conditions like acne, psoriasis, and eczema by reducing inflammation and fighting bacteria on the skin’s surface.
Perez et al., 2022. In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties. This study explored CBG’s antioxidant and anti-inflammatory effects, demonstrating that CBG reduced reactive oxygen species and cytokine release, outperforming CBD in some cases. A clinical trial confirmed CBG’s efficacy in reducing skin irritation and improving barrier function.
Wroński et al., 2024. Modulation of Redox and Inflammatory Signaling in Human Skin Cells Using Phytocannabinoids Applied after UVA Irradiation: In Vitro Studies.
This study analyzed the combined effects of CBG and CBD on skin cells exposed to UVA. CBG helped reduce oxidative stress and inflammatory responses, indicating its protective effects on skin health.
